Institute for Advanced and Applied Chemical Synthesis
Institute for Advanced and Applied Chemical Synthesis
Associate Research Fellow
E-mail：yajianhu@jnu.edu.cn
Personal Website：
PhD, Associate Research Fellow. His research interests include total synthesis of bioactive natural products and natural product inspired synthetic methodology development. As first/co-first author, he has published more than 10 peer-reviewed papers in prestigious scientific journals, such as Chem. Rev., Chem. Soc. Rev., Nat. Prod. Rep., J. Am. Chem. Soc., Org. Lett., and Org. Chem. Front.. Notably, during his PhD study, he completed the total synthesis the famous anti-tumor natural medicine Taxol. In January 2022, he joined Jinan University as an associate research fellow.
Jan 2022 - present: Associate Research Fellow
Institute for Advanced and Applied Chemical Synthesis, Jinan University
Sep 2016 - Jun 2021: Ph.D. in Biomedical Sciences
Institute of Chinese Medical Sciences, University of Macau (with Prof. Chuang-Chuang Li and Prof. Jing Zhao)
Jul 2015 - Aug 2016: Research Assistant
Department of Chemistry, Southern University of Science and Technology (with Prof. Chuang-Chuang Li)
Sep 2012 - Jun 2015: M.S. in Medicinal Chemistry
Department of Natural Product Chemistry, China Pharmaceutical University (with Prof. Ling-Yi Kong)
Sep 2008 - Jun 2012:B.S. in Bioengineering
College of Life Sciences, Heilongjiang Bayi Agricultural University
# denotes “co-first author”; * denotes “corresponding author”.
1. Ya-Jian Hu,# Chen-Chen Gu,# Xin-Feng Wang,# Long Min, Chuang-Chuang Li.* Asymmetric Total Synthesis of Taxol. J. Am. Chem. Soc.2021, 143, 17862-17870. (IF = 15.419)
2. Jian-Hong Fan,#Ya-Jian Hu,# Li-Xuan Li,# Jing-Jing Wang,# Shao-Ping Li, Jing Zhao,* Chuang-Chuang Li.*Recent advances in total syntheses of natural products containing the benzocycloheptane motif. Nat. Prod. Rep.2021, 38, 1821-1851. (IF = 13.423)
3. Ya-Jian Hu,# Li-Xuan Li,# Jing-Chun Han,# Long Min,# Chuang-Chuang Li.*Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009–2019). Chem. Rev.2020,120, 5910-5953. (IF = 60.622)
4. Long Min,#Ya-Jian Hu,# Jian-Hong Fan,#Wen Zhang,#Chuang-Chuang Li.* Synthetic applications of type II intramolecular cycloadditions. Chem. Soc. Rev.2020, 49, 7015-7043. (IF = 54.564)
5. Jian-Hong Fan,#Ya-Jian Hu,# Qiang Guo, Shaoping Li, Jing Zhao,* Chuang-Chuang Li.* Asymmetric synthesis of the tetracyclic core of bufogargarizin C by an intramolecular [5+ 2] cycloaddition. Org. Chem. Front.2019, 6, 22-26. (IF = 5.155)
6. Ya-Jian Hu,# Jian-Hong Fan,# Shaoping Li, Jing Zhao,* Chuang-Chuang Li.* Synthetic Study toward the Total Synthesis of Taxezopidines A and B. Org. Lett.2018, 20, 5905-5909. (IF = 6.555)
7. Xin Liu,#Ya-Jian Hu,# Jian-Hong Fan,#Jing Zhao,* Shaoping Li,* Chuang-Chuang Li.*Recent synthetic studies toward natural products via [5+2] cycloaddition reactions. Org. Chem. Front.2018, 5, 1217-1228. (IF = 5.076)
8. Xin Liu,#Ya-Jian Hu,# Bo Chen,# Long Min, Xiao-Shui Peng, Jing Zhao,* Shaoping Li,* Henry N. C. Wong, Chuang-Chuang Li.*Asymmetric Total Syntheses of Colchicine, β-Lumicolchicine, and Allocolchicinoid N-Acetylcolchinol-O-methyl Ether (NCME). Org. Lett.2017, 19, 4612-4615. (IF = 6.492)
9. Bo Chen,# Xin Liu,#Ya-Jian Hu, Dong-Mei Zhang,Lijuan Deng,Jieyu Lu,Long Min, Wen-Cai Ye, Chuang-Chuang Li.*Enantioselective total synthesis of (−)-colchicine, (+)-demecolcinone and metacolchicine: determination of the absolute configurations of the latter two alkaloids. Chem. Sci.2017, 8, 4961-4966. (IF = 9.063)
10. Ya-Jian Hu, Xiao-Bing Wang,* Su-Yi Li, Sai-Sai Xie, Kelvin D. G. Wang, Ling-Yi Kong.* Facile synthesis of spiro chromanone-tetrahydrothiophenes with three contiguous stereocenters via sulfa-Michael/aldol cascade reactions. Tetrahedron Lett.2015, 56, 105-108. (IF = 2.347)
11. Ya-Jian Hu, Neng Jiang, Sai-Sai Xie, Su-Yi Li, Jin-Shuai Lan, Ling-Yi Kong,* Xiao-Bing Wang.* Iodine-promoted sequential Michael and oxidative dehydrogenation processes: synthesis of trisubstituted methanes containing a coumarin and a chromone ring. Tetrahedron2015, 71, 8026-8032. (IF = 2.645)
Room 617, the Second Science and Technology Building, Jinan University, Guangzhou
Email: yajianhu@jnu.edu.cn
