Institute for Advanced and Applied Chemical Synthesis

Hui Xian Tan

Research Fellow

E-mail:shenhxtan@gmail.com

Personal Website:

Education


May2011–Jul 2015:PhD–Organic Chemistry

The Australian National University, Canberra, Australia at the Research School of Chemistry working under the supervision of  Professor Martin Banwell 

Jan–Dec2010:Bachelor of Science (Honors)–Medicinal Chemistry

The University of Auckland, Auckland, NewZealand

  Awarded First Class Honors

Jul2006–Dec2009:Bachelor of Biomedical Science–Molecular Pharmacology and Medicinal Chemistry

Victoria University of Wellington, Wellington, New Zealand 

University of California,SanDiego, U.S.A.(FallQuarter, 2009)

  Education Abroad Reciprocal Exchange Program

  Awarded Provost Honors (GPA4.0/4.0)

Employment

Jul 2020 – Present: Research Fellow

JINAN UNIVERSITY, Guangzhou, China at the Institute for Advanced and Applied Chemical Sciences (IAACS)●  Development of synthetic methods towards broad-spectrum anti-coronavirus Amaryllidaceae alkaloids

  Supervisory and mentorship role within the research group to provide support to graduate students conducting research

  Review and edit research articles

Jan 2018 – May 2020: Product and Sales Consultant

HOSPRO, Malacca, Malaysia

  Manage relations between clients and stakeholders to achieve business and public health outcomes

  Assist with accounts and delivery of services to public hospitals

  Drawing on my scientific knowledge to source hospital amenities on the international market that both achieved patient outcomes and respected international regulatory requirements

  Working independently as part of an international team of Consultants

Jan – Jun 2017: Postdoctoral Fellow – Medicinal Chemistry

SUN YAT-SEN UNIVERSITY, Guangzhou, China at the School of Pharmaceutical Sciences

  Development of small molecules to target Alzheimer’s Disease

  Supervisory and mentorship role within the research group to provide support to graduate students conducting research

  Review and edit research articles

Jan – Dec 2016: Research Assistant – Organic Chemistry

THE AUSTRALIAN NATIONAL UNIVERSITY, Canberra, Australia at the Research School of Chemistry working under the supervision of Professor Martin Banwell

  Development of new methods in the synthesis of biologically active natural products

  Collation of scientific data and preparation of research articles to be published

Jan – Dec 2016: Grants Officer

THE AUSTRALIAN NATIONAL UNIVERSITY, Canberra, Australia

(within the Science Administrations Research Management Team)

  Assist with the collection and integrity of data on the research management system ARIES

  Provide support for the submission of Australian Research Council (ARC) and National Health and Medical Research Council (NHMRC) funding applications

  Conduct compliance reviews of funding applications

Awards

Chinese Acade my of Sciences Postdoctoral Fellowship Overseas High- LevelAcademicTalents (China)(2017)  

Student Poster Prizeat the Southern Highlands Conference on Heterocyclic Chemistry(2012)

International Postgraduate Research Scholarship (2011-2014)

University of California,San Diego Provost Honors(2009)

The Australian National University Summer Research Scholarship(2008)


Publications

1. Chen Qi; Lan Ping; Tan Shen (Hui-Xian)*; Banwell Martin G.*, The Palladium-Catalyzed Glycosylation of                  Halotropones. Org. Lett., 2023, 25, 284−288.

2. Tan Shen (Hui-Xian); Chen, Qi; Lan, Ping; Banwell, Martin G.* Troponoid compounds as therapeutic agents and as      targets and templates for chemical synthesis. Synlett. 2022, 33, 1968–1990.

3. Tan Shen (Hui-Xian); Lan, Ping; Banwell, Martin G.; White, Lorenzo V.* Practical, multigram preparation of                synthetically useful, enantiomerically pure building-blocks from quinic acid. SynOpen, 2022, 6, 306–311.

4. S. Tan, Y.-T. He, P. Lan, M.G. Banwell and L. V. White, A Seven Step Total Synthesis of (–)-Thebaine, Synthesis,          published online 21 September 2022 (doi: 10.1055/a-1948-3335)

5. L. Yi, Y. He, S. Tan, L. V. White, P. Lan, M. G. Gardiner, Z. Pei, M. L. Coote and M. G. Banwell, Total Syntheses of      the Structures Assigned to the Marine Natural Products Orthoscuticellines A-E, J. Org. Chem. 2022, 87, 12287.

6. S. Tan, M. Karuppasamy, P. Lan, Y. Zhang, Hu, X. Lai, B. S.-C. Lim, W. Liu, 」. chen, E.-H.Chew and  M. G.                Banwella, Ribisins and Certain Analogues Exert Neuroprotective EffectsThrough Activation of the Keap-Nrf2-ARE      Pathway, Chem. Med. Chem. 2022, 17, e202200292.