Institute for Advanced and Applied Chemical Synthesis
Institute for Advanced and Applied Chemical Synthesis
Research Fellow
E-mail：Lorenzo.white@sydney.edu.au
Personal Website：
Current Location | Sydney, Australia. |
Lorenzo.white@sydney.edu.au | |
Phone | (+61) 0480 411 192 |
Place and Date of Birth | Canberra, Australia, 14/02/1987 |
Citizenships | Dual Australian and Italian citizen |
Languages | Native English, Fluent Italian Intermediate Chinese (HSK4) Intermediate French (B1) |
www.linkedin.com/in/lorenzo-white-chemist |
Education
2012 – 2016 PhD in Organic Chemistry.
Thesis title: ‘Stereochemical Control in Complex Molecule Synthesis.’
Supervisor: Professor Martin Banwell, Research School of Chemistry, Australian National University, Canberra, Australia.
2015 Doctoral Research Exchange Programme.
Completed under the supervision of Professor Samir Zard, Laboratoire LSO,
École Polytechnique, Paris, France.
2006 – 2011 Bachelor of Science with Honours (1st Class).
Final honours mark 93/100.(awarded best honours thesis in Chemistry).
Chemistry double major – high distinction average.
Australian National University, Canberra, Australia.
2006 – 2010 Bachelor of Arts.
Philosophy major, Italian major – distinction averages.
Australian National University, Canberra, Australia.
Awards and Research Grants
2023 “Special Prize” for Best Oral Communication. A. Corbella International Organic Chemistry Conference, Gargnano, Italy.
2023 International Collaboration “Special Program” Grant. Research grant awarded by the Chinese Central Government Ministry of Science and Technology valued at 150 000 RMB per year. I was the first applicant in China to receive this grant.
2022 National Science Foundation of China (NSFC) Research Grant. Prestigious research grant awarded by the National Science Foundation of China valued at 400 000 RMB over two years.
2020 & 2021 Foreign Young Scientist Innovation Grant. Research grant awarded by the Chinese Central Government Ministry of Science and Technology valued at 250 000 RMB per year.
2016 Pearl River Foreign Young Talent Attraction Grant. ¥600 000 RMB research grant awarded by the Guangdong Province, China. Only 5 applicants were successful in 2016.
2015 Vice-Chancellor's HDR Travel Grant. Australian National University.
2012 AM Sargeson Award for Excellence in Chemistry. Australian National University.
2011 Adrian Albert Award (for Best Honours Thesis in Chemistry). Australian National University.
2008 & 2009 ANU Chancellor’s Award (for Outstanding Performance in Undergraduate Studies). Australian National University.
Recent Professional Experience
2023 – 2024
Visiting Research Fellow, École Polytechnique (Paris, France).
Appointment as an Independent Research Fellow working in collaboration with Professor Sam Zard within the Laboratoire de Synthèse Organique. Research focuses include the development of new organic reactions mediated by radicals and carbenes and the application of the radical chemistry of xanthates to the synthesis of complex natural products.
2020 – 2024
“High Level Foreign Talent” Research Fellow, Jinan University (Guangzhou, China).
Carrying out original scientific researcher based on an independently devised research programme. The position involves the daily practical elaboration of advanced organic chemistry techniques in the laboratory as well as composing articles for internationally recognised scientific journals and grant applications for National Chinese scientific bodies. In addition, the role involves extensive supervisory work of PhD and master’s candidates.
Publications
1) Biomimetic and Concise Total Syntheses of Prenylated and Bicyclo[2.2.2]diazaoctaneContaining Indole Alkaloids Including Taichunamide A, Notoamide N and Versicolamide B. Z. Xu, X. T. Liang, Lorenzo V. White, M. G. Banwell* and S. Tan* Org. Lett. 2024, 26, 5989.
2) Synthesis of 4-Alkyl-2-chloro Imidazoles Using Intermolecular Radical Additions. S. Tan, V. S. Dorokhov, Lorenzo V. White* and S. Z. Zard*. Org. Lett. 2024, 26, 5989.
3) Short Formal Syntheses of Lycorine and Congeners Using a 5-Endo-Trig/6-Endo-Trig Radical Cyclization Sequence. S. Tan, S. Z. Zard, L. N. Pham, M. L. Coote, M. G. Banwell P. Lan and Lorenzo V. White*. Org. Lett. 2024, 26, 4292.
4) Total Syntheses of the Structures Assigned to Denigrins A, B, C, F, 2 and G, 3,4-DiarylPyrrole and -Pyrrolidinone Alkaloids, and the Conversion of Congener B into the Cometabolite Spirodactylone. L. Yi, S. Tan, Lorenzo V. White, M. Y. Liang and M. G. Banwell*. J. Nat. Prod. 2024, 87, 1521.
5) Visible Light-mediated Syntheses of Unsymmetrical Methylene-bridged bis-Heterocycles via an Alkoxy Radical Relay Reaction. T. T. Yuan, J. Chen, L. N. Pham, S. Paul, Lorenzo V. White, J. Li, P. Lan, M. L. Coote, M. G. Banwell, P. Lan and Y.-T. He.* Org. Chem. Front. 2023, 10, 4649.
6) The Useful Biological Properties of Sucrose Esters: Opportunities for the Development of New Functional Foods. Y. Teng, P. Lan, M. G. Banwell* and Lorenzo V. White.* Crit. Rev. Food Sci. Nutr. Published online 17 April 2023. DOI: 10408398.2023.2194438.
7) Syntheses and Preliminary Biological Evaluation of the Dibromopyrrole-Containing Marine Natural Products Agesasine A, Agesasine B, Longamide E and Various Congeners . C. Chen, T. T. Yuan, P. Lan, Lorenzo V. White, J. Chen* and M. G. Banwell.* Eur. J. Org. Chem. 2023, 26, e202300003.
8) Total Syntheses of Dysidealactams E and F and Dysidealactone B, Drimane-type Sesquiterpenes Derived from a Dysidea sp. of Marine Sponge. Y. Chen, P. Lan, Lorenzo V. White, W. Yang and M. G. Banwell*.
Synlett 2023, 34, 1529.
9) A Seven Step Total Synthesis of (–)-Thebaine. S. Tan, Y.-T. He, P. Lan, M. G. Banwell* and Lorenzo V. White.* Synthesis 2023, 55, 1700.
10) Six-Step Total Syntheses of (–)-Galanthamine and (–)-N-Norgalanthamine. N. Hu, Y.-T. He, P. Lan, M. G. Banwell* and Lorenzo V. White.* Aust. J. Chem. 2022, 75, 974.
11) Creativity and the Synthesis of Ideas. Lorenzo V. White.* Chemistry in Australia (Feature article, published online 1 December 2022).
12) Practical, Multigram Preparation of Synthetically Useful, Enantiomerically Pure Building Blocks from Quinic Acid. S. Tan, P. Lan, M. G. Banwell* and Lorenzo. V. White.* SynOpen 2022, 6, 306.
13) Chemoenzymatic Total Syntheses of (+)- and (–)-Aspidophytine from a Common, Homochiral Precursor. M. G. Banwell,* Lorenzo V. White and S. Ye.* J. Org. Chem. 2022, 87, 14407.
14) Investigation of the Emulsifying and In Vitro Digestive Properties of High-Purity Sucrose Mono-Stearate Esters. J.-Q. Chen, M.-Y. Liang, C. Qing, Y. Teng, Lorenzo V. White, M. G. Banwell, A. Li, Y. Wang and P. Lan.* ACS Food Sci. Technol. 2022, 2, 1662.
15) Solasodine Suppresses MCF7 Breast Cancer Stem-Like Cells via Targeting Hedgehog/Gli1. J. Chen, D. Ma, C. Zeng, Lorenzo V. White, H. Zhang, Y. Teng, P. Lan*. Phytomedicine 2022, 107, 154448.
16) Total Syntheses of the Structures Assigned to the Marine Natural Products. Orthoscuticellines A-E. L. Yi, Y. He, S. Tan, Lorenzo V. White, P. Lan, M. G. Gardiner, Z. Pei, M. L. Coote and M. G. Banwell.*J. Org. Chem. 2022, 87, 12287.
17) Expeditious Access to Morphinans by Chemical Synthesis. Lorenzo. V. White, N. Hu, Y.-T. He, M. G. Banwell* and P. Lan.*Angew. Chem. Int. Ed. 2022, 61, e202203186.
18) The Inhibition of RNA Virises by Amaryllidadeae Alkaloids: Opportunities for the Development of Broad- Spectrum Anti-Coronavirus Drugs. S. Tan, M. G. Banwell, W.-C. Ye, P. Lan, Lorenzo. V. White.* Chem. Asian J. 2022, 17, e202101215.
19) Enzymatic Synthesis of a Homologous Series of Long- and Very Long-Chain Sucrose Esters and Evaluation of Their Emulsifying and Biological Properties. J.-P. Zhu, M.-Y. Liang, Y.-R.Ma, Lorenzo.V.White, M. G. Banwell, Y. Teng and P. Lan.* Food Hydrocoll. 2022, 124 (Part A), 107149.
20) Solvent-Free Synthesis of High-Purity Sucrose Fatty Acid Mono-Esters and a Comparison of their Properties with those of their Commercial Counterparts. M.-F. Xie, Lorenzo. V. White, M. G. Banwell, Y. Wang and P. Lan.* ACS Food Sci. Technol. 2021, 1, 1550.6
21) The Chemical Synthesis of the Crinine and Haemanthamine Alkaloids: Biologically Active and Enantiomerically-Related Systems that Serve as Vehicles for Showcasing New Methodologies for Molecular Assembly . N. Hu, Lorenzo V. White, P. Lan and M. G. Banwell.* Molecules 2021, 26, 765.
22) Quantitative Proteomics Reveals Cellular Off-targets of a DDR1 Inhibitor. J. Xu, Z. Zhang, L. Lin, H. Sun, Lorenzo V. White, K. Ding* and Z. Li.* ACS Med. Chem. Lett. 2020, 11, 535.
