Profile

PhD, Associate Research Fellow, Master degree supervisor. Her research focus is evaluation compounds’ effects on anti-inflammation, anti-cancer, anti-obesity in vitro and in vivo as well as fabrication of delivery system to improve the bioavailability of liposoluble compounds in vitro and in vivo.She has published more than30 peer-reviewed papers in international journals, of which 20 she serves as the first/corresponding authors, mainly in top journals such as Journal of Agricultural and Food Chemistry, Food & function, Phytomedicine andJournal of Functional Foods and so on. She presided over 1 National Natural Science Foundation of China and 6 provincial and ministerial projects.

Education& Professional Experience：

2020.05-present

Associate Research Fellow, Institute for Advanced and Applied Chemical Synthesis, Jinan University

2015.09-2020.02

PhD of Food Chemistry

Department of Food Science and Technology, Chung-Ang University, Korea;

2012.09-2015.06

Master of Food Science

College of Food Science & Technology, Nanchang University, China;

2008.09-2008.06

Bachelor of Food Science & Engineering

College of Life Science, Shaanxi University of Science and Technology, China

Representative Publications in Recent 5 Years：

1.   Chen, J., Li, W., Lee, Y. Y., Cai, Z., Chen, J., & Wang, Y. (2023). The synergistic treatment of cyclolinopeptide J and calcium carbonate nanoparticles for osteoporosis via BMP/Wnt signaling: In vivo and in vitro. Journal of Functional Foods, 110, 105826. (Corresponding Author)

2.   Zhang, X., Chen, J., Zhou, S., Jiang, Y., Wang, Y., & Li, Y. (2024). The effect of flaxseed oil after deep frying on lipid metabolism and gut barrier homeostasis. Food Research International, 175, 113728. (First Author)

3.   Zheng D, Guan W, Chen J, et al. (2024). Sucrose Stearates Stabilized Oil-in-Water Emulsions: Gastrointestinal Fate, Cell Cytotoxicity and Proinflammatory Effects after Simulated Gastrointestinal Digestion. Foods, 13(1): 175. (Corresponding Author)

4.   Yuan, T. T., Chen, J., Paul, S., White, L. V., Li, J., Lan, P., ... & He, Y. T. (2023). Visible light-mediated syntheses of unsymmetrical methylene-bridged bis-heterocycles via an alkoxy radical relay reaction. Organic Chemistry Frontiers, 10(18), 4649-4657. (First Author)

5.   Li, J., Wang, J., Zhang, N., Li, Y., Cai, Z., Li, G., ... & Chen, J. (2023). Anti-aging activity and their mechanisms of natural food-derived peptides: current advancements. Food Innovation and Advances, 2(4), 272-290. (Corresponding Author)

6.   Kim, J. T., Chen, J., Zhou, Y., Son, M. J., Jeon, D. H., Kwon, J. W., ... & Lee, H. J. (2024). Cycloastragenol inhibits adipogenesis and fat accumulation in vitro and in vivo through activating Hedgehog signaling. Food Science and Biotechnology, 33(3), 711-720. (First Author)

7.   Li, J., Zeng, C., Huang, Q., Zheng, M. M., Chen, J., & Ma, D. (2023). Control release of α-mangostin by a novel dual-polysaccharides delivery system for colitis treatment under simulated gastrointestinal conditions. Food Bioscience, 102531. (Corresponding Author)

8.   Chen, C., Yuan, T., Lan, P., White, L. V., Chen, J., & Banwell, M. G. (2023). Syntheses and Preliminary Biological Evaluations of the Dibromopyrrole‐Containing Marine Natural Products Agesasine A, Agesasine B, Longamide E and Various Congeners. European Journal of Organic Chemistry, e202300003 (Corresponding Author).

9.   Chen, J., Ma, D., Zeng, C., White, L. V., Zhang, H., Teng, Y., & Lan, P. (2022). Solasodine suppress MCF7 breast cancer stem-like cells via targeting Hedgehog/Gli1. Phytomedicine, 154448. (First Author) 

10. Zhou, Y., Qiu, S., Kim, J. T., Lee, S. B., Park, H. J., Son, M. J., ... & Chen, J. * (2022). Garcinone C Suppresses Tumorsphere Formation and Invasiveness by Hedgehog/Gli1 Signaling in Colorectal Cancer Stem-like Cells. Journal of Agricultural and Food Chemistry, 70(26), 7941-7952. (Corresponding Author)

11. Tan, S.H., Karuppasamy, M., Lan, P., Zhang, Y., Hu, J., Lai, X., Lim, B.S.C., Liu, W., Chen, J. *, Chew, E.H. and Banwell, M., (2022.). Ribisins and Certain AnaloguesExert Neuroprotective Effects Through Activation of the Keap‐Nrf2‐ARE Pathway. ChemMedChem. (Corresponding Author)

12. Qiu, S., Zhou, Y., Kim, J. T., Bao, C., Lee, H. J., & Chen, J. * (2021). Amentoflavone inhibits tumor necrosis factor-α-induced migration and invasion through AKT/mTOR/S6k1/hedgehog signaling in human breast cancer. Food & Function, 12, 10196-10209. (Corresponding Author)

Contact：

Room 620, the Second Science and Technology Building, Jinan University, Guangzhou