Institute for Advanced and Applied Chemical Synthesis

Yu-Tao He

Associate Professor

E-mail:heyutao7@jnu.edu.cn

Personal Website:

Profile


Associate Professor, Master degree supervisor. Dr. Yu-Tao He received his Ph. D. at Lanzhou University in 2016 under the guidance of Prof. Yong-Min Liang.He then moved to Korea Advanced Institute of Science and Technology (KAIST) asa post-doctorunder the supervision of Prof. Sungwoo Hong. In 2019, he joined Prof. Julia Khusnutdinova’s group at Okinawa Institute of Science and Technology Graduate University (OIST) as a post-doctoral Scholar.In 2020, he moved back to China, and joined Institute for Advanced and Applied Chemical Synthesis at Jinan University. His research is focus on the organic synthesis methodology, including photochemistry, transition metal catalysis, asymmetric synthesis, medicinal chemistry and radical chemistry. He was supported by the Grant-in-Aid for Scientific Research (KAKENHI) as a Principal Investigator in Japan. As of October 2023, he has published more than 30 peer-reviewed papers in international journals, of which 15 he serves as the first author or corresponding author, mainly in top journals such as Angewandte Chemie International Edition, Green Chemistry, Organic Letters, Chemical Communications, Advanced Synthesis & Catalysis, Organic Chemistry Frontiers, and Organometallics.

 

Education& Professional Experience

2020.11-present 

Associate Professor, Institute for Advanced and Applied Chemical Synthesis, Jinan University

2019.04-2020.11 

Postdoctoral Scholar, Okinawa Institute of Science and Technology Graduate University (OIST)

2017.04-2019.04 

Postdoctoral Scholar, Korea Advanced Institute of Science and Technology (KAIST)/Institute for Basic Science (IBS)

2011.09-2016.06 

Ph.D in Organic Chemistry, Lanzhou University,

2009.07-2011.07 

Technician, Tianhua Institute of Chemical Machinery & Automation

2005.09-2009.06 

Bachelor of Engineering (Chemical Engineering and Technology), Lanzhou University


Representative Publications

1.     T.-T. Yuan, J. Chen, L. N. Pham, L. V. White, P. Lan, M. L. Coote, M. G. Banwell,* Y.-T. He*. Visible Light-induced Syntheses of Unsymmetrical Methylene-bridged bis-Heterocycles via an Alkoxy Radical Relay Reaction. Org. Chem. Front. 2023, 10, 4649.

2.     Y. Chen,# G.-Y. Zhang,# C. Guo, P. Lan, M. G. Banwell*, Y.-T. He*. Silver-Promoted Radical Ring-Opening/Pyridylation of Cyclobutanols with N-Methoxypyridinium Salts. Chem. Eur. J. 2022, 28, e202104627.

3.     Y.-T. He, L.-X. Li, X. Lin, B.-L. Hou*, C.-C. Li*. Synthesis of Various Bridged Ring Systems via Rhodium-Catalyzed Bridged (3+2) Cycloadditions. Org. Lett. 2022, 24, 186.

4.     Y.-T. He, A. Karimata, O. Gladkovskaya, E. Khaskin, R. R. Fayzullin, A. Sarbajna, and J. R. Khusnutdinova*C–C Bond Elimination from High-Valent Mn Aryl Complexes. Organometallics2021, 40, 2320.

5.     J. Jeon,# Y.-T. He#, S. Shin, S. Hong*. Visible-Light-Induced Remote Pyridyl ortho-Migration for Trifluoromethylative Pyridylation of Unactivated Alkenes. Angew. Chem. Int. Ed. 2020, 59, 281.

6.     A. Sarbajna,#Y.-T. He#, M. H. Dinh, O. Gladkovskaya, S. M. W. Rahaman, A. Karimata, E. Khaskin, S. Lapointe, R. R. Fayzullin, J. R. Khusnutdinova*. Aryl-X Bond-Forming Reductive Elimination from High-Valent Mn-Aryl Complexes. Organometallics2019, 38, 4409.

7.     Y.-T. He, D. Kang, I. Kim, S. Hong*. Metal-Free Photocatalytic Trifluoromethylative Pyridylation of Unactivated Alkenes. Green Chem. 2018, 20, 5209.

8.     Y.-T. He, J. Won, J. Kim, B. Park, T. Kim, M.-H. Baik*, S. Hong*. One-Pot Bifunctionalization of Unactivated Alkenes, P(O)–H Compounds, and N-Heteroarenium Salts for the Construction of β-Pyridyl Alkylphosphonates. Org. Chem. Front. 2018, 5, 2595.

9.     Y.-T. He, L.-H. Li, Q. Wang, W. Wu, Y.-M. Liang* Synthesis of β-Difluoroalkylated Acrylonitriles in the Presence of Copper Powder. Org. Lett. 2016, 18, 5158.

10.  Y.-T. He, Q. Wang, L.-H. Li, X.-Y. Liu, P.-F. Xu, Y.-M. Liang* Palladium-Catalyzed Intermolecular Aryldifluoromethylation of Alkynes. Org. Lett.2015, 17, 5188.

11.  Y.-T. He, Q. Wang, J. Zhao, X.-Z. Wang, Y.-F. Qiu, Y.-C. Yang, J.-Y. Hu, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl-Substituted Spiro-2H-azirines from 1,6-Enynes. Adv. Synth. Catal. 2015, 357, 3069.

12.  Y.-T. He, Q. Wang, J. Zhao, X.-Y. Liu, P.-F. Xu, Y.-M. Liang* The copper-catalyzed synthesis of β-trifluoromethylated acrylonitriles and trifluoromethyl-substituted 2H-azirines. Chem. Commun. 2015, 51, 13209.

13.  Y.-T. He, L.-H. Li, Z.-Z. Zhou, H.-L. Hua, Y.-F. Qiu, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Three-Component Cyanotrifluoromethylation/Azidotrifluoromethylation and Carbocyclization of 1,6-Enynes. Org. Lett. 2014, 16, 3896.

14.  Y.-T. He, L-H. Li, Y.-F. Yang, Z.-Z. Zhou, H.-L. Hua, X.-Y. Liu, Y.-M. Liang* Copper-Catalyzed Intermolecular Cyanotriuoromethylation of Alkenes. Org. Lett.2014, 16, 270.

15.  Y.-T. He, L.-H. Li, Y.-F. Yang, Y.-Q. Wang, J.-Y. Luo, X.-Y. Liu, Y.-M. Liang* Copper-catalyzed synthesis of trifluoromethyl-substituted isoxazolines. Chem. Comm.2013, 49, 5687.


Contact

Room 617, the Second Science and Technology Building, Jinan University, Guangzhou


Email:heyutao7@jnu.edu.cn